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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 287331Generated: October 24, 2026

1-(Thien-2-ylcarbonyl)piperazine → 6-Chloro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazine-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrile

https://huagongshe.com/en/reaction/287331

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Thien-2-ylcarbonyl)piperazineHCID 797562—
Reactant4,6-Dichloro-2-oxo-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrileHCID 69217446—
Product6-Chloro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazine-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrileHCID 69218376—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (8/10)
ORD IDord-ff85f0f690d5417788f9cd1842eff1fc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (8/10)