HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 287331Generated: October 24, 2026
1-(Thien-2-ylcarbonyl)piperazine → 6-Chloro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazine-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrile
https://huagongshe.com/en/reaction/287331
Participants
| Role | Name | HCID | Charge |
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| Reactant | 1-(Thien-2-ylcarbonyl)piperazine | HCID 797562 | — |
| Reactant | 4,6-Dichloro-2-oxo-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrile | HCID 69217446 | — |
| Product | 6-Chloro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazine-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrile | HCID 69218376 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
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| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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| ORD ID | ord-ff85f0f690d5417788f9cd1842eff1fc |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (8/10) |
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