HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | N-(1-Cyanocyclopentyl)pentanamide | HCID 11790092 | — |
| Product | 2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-one | HCID 10176511 | — |
Reaction Steps
To 19.6 g (0,1 mol) of 1-cyano-1-n-pentanoylaminocyclopentane dissolved in 70 ml of methanol, 5 g of Varion AD resin was added the reaction mixture was heated under reflux conditions for 3 hours. After filtration and evaporation 16.5 g (71.7%) of title compound was obtained, assay by GC: 92%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06211382B1 |
| Source dataset | uspto-grants-2001_04 |
| ORD ID | ord-0e035a38a6d2411897178fb37aeacd16 |
| Source note | uspto-grants-2001_04 |