HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 342221Generated: October 24, 2026
Potassium Carbonate → 7-(4-bromo-but-2-enyloxy)-4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazine
https://huagongshe.com/en/reaction/342221
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | trans-1,4-Dibromo-2-butene | HCID 641245 | — |
| Reactant | 4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazin-7-ol | HCID 135501633 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 7-(4-bromo-but-2-enyloxy)-4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazine | HCID 67684159 | 78.3% |
Reaction Steps
A mixture of 1.28 g of 4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazin-7-ol, 2.71 g of (E)-1,4-dibromo-2-butene and 1.74 g of potassium carbonate in 80 ml of acetone is stirred at 65° C. After cooling the reaction mixture is filtered and the filtrate is concentrated and purified by chromatography (silica gel, toluene/acetone 98:2). There are obtained 1.44 g of 7-(4-bromo-but-2-enyloxy)-4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazine, MS: m/e 437 (64%, M+, 2 Br).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05856503 |
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| Source dataset | uspto-grants-1999_01 |
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| ORD ID | ord-a8dd78e614b643caa44ffaa4cc4cd5ae |
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| Source note | uspto-grants-1999_01 |
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