HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 2-[2-(Diethylamino)ethyl]-6-phenyl-isothiazolo[5,4-d]pyrimidin-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | HCID 178418472 | HCID 178418472 | — |
| Product | 2-[2-(Diethylamino)ethyl]-6-phenyl-isothiazolo[5,4-d]pyrimidin-3(2H)-one | HCID 9905503 | 68.5% |
Reaction Steps
Using the procedure of Example 20, 3.3 g (0.01 mol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid (2-diethylamino-ethyl)-amide (from Preparation 36) and 2.54 g (0.01 mol) of iodine were reacted to give 2.25 g of the title compound after recrystallization from isopropanol, mp 106-107° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133270 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-7f01d8b4285645a59fd4fbacebdeec3e |
| Source note | uspto-grants-2000_10 |