HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylsulfonyl)phenylhydrazine hydrochloride → 6-methyl-2-[1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazol-5-yl]benzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylsulfonyl)phenylhydrazine hydrochloride | HCID 2735181 | — |
| Reactant | 1-(6-Methylbenzothiazol-2-yl)-4,4,4-trifluorobutane-1,3-dione | HCID 23285377 | — |
| Product | 6-methyl-2-[1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazol-5-yl]benzothiazole | HCID 23285360 | 47% |
Reaction Steps
The procedure of Example 9 was repeated using 1-(6-methylbenzothiazol-2-yl)-4,4,4-trifluorobutane-1,3-dione and 4-methylsulfonylphenylhydrazine hydrochloride as the starting materials to obtain 6-methyl-2-[1-(4-methylsulfonylphenyl)-3-trifluoromethyl-1H-pyrazol-5-yl]benzothiazole (yield, 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06136831 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-aed63c40e69b48dd8503aab103eb26bc |
| Source note | uspto-grants-2000_10 |