HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydrazinylbenzenesulfonamide hydrochloride → 4-[5-(7-fluorobenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydrazinylbenzenesulfonamide hydrochloride | HCID 2794567 | — |
| Reactant | 1-(7-Fluorobenzothiazol-2-yl)-4,4,4-trifluorobutane-1,3-dione | HCID 23285428 | — |
| Product | 4-[5-(7-fluorobenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide | HCID 23285373 | 88% |
Reaction Steps
The procedure of Example 9 was repeated using 1-(7-fluorobenzothiazol-2-yl)-4,4,4-trifluorobutane-1,3-dione and 4-sulfamoylphenylhydrazine hydrochloride as the starting materials to obtain 4-[5-(7-fluorobenzothiazol-2-yl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide (yield, 88%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06136831 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-ee87f12a5e074065bc4d1fc3b61958c0 |
| Source note | uspto-grants-2000_10 |