HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitroisophthalic acid → 4-Aminobenzene-1,3-dioic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitroisophthalic acid | HCID 3062438 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Aminobenzene-1,3-dioic acid | HCID 11355852 | 87% |
Reaction Steps
To a solution of 4-nitro isophthalic acid (98 g, 0.457 mol) in methanol (5 L) was added Pd/C (20%) and hydrogenated at RT for 4 h. The reaction mixture was filtered through celite and filtrate concentrated under vacuum to give 4-amino isophthalic acid (72 g, 87%) as a solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106214B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-cfbdf63e2ce043f4bfa7dd3fb1708429 |
| Source note | uspto-grants-2012_01 |