3-Nitrophthalic acid → 3-nitro-N-hydroxyphthalimide

HRID 429529

Reaction equation

HRID 429529 reaction equation
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:6]([C:7](O)=[O:8])[C:5]=1[C:13]([OH:15])=O)([O-:3])=[O:2].P([O-])([O-])([O-])=O.[OH:21][NH3+:22].O[NH3+].O[NH3+]>>[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[C:6]2[C:7]([N:22]([OH:21])[C:13](=[O:15])[C:5]=12)=[O:8])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 690433-Nitrophthalic acidHCID 10176537Hydroxylammonium phosphate (3:1)

Product 1

HCID 46592203-nitro-N-hydroxyphthalimide

Procedure

Analogous to Example 4, but from 500 mg (2.37 mmol) of 3-nitrophthalic acid and 187 mg (0.947 mmol) of hydroxylammonium phosphate at a bath temperature of 130° C. The yield was 443 mg (90%).

Workup

  1. customtemperature of 130° C

Sources & evidence

ORD record
ord-b5b27bf38b6943a2b32bc2ef19e358e4
Source dataset
uspto-grants-2001_11
Patent number
US06316639B1

Linked notes

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