HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → (1-benzyl-1H-imidazol-2-yl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Benzylimidazole | HCID 77918 | — |
| Product | (1-benzyl-1H-imidazol-2-yl)methanol | HCID 311778 | — |
Reaction Steps
A mixture of 1-benzyl-imidazole (5 g, 32 mmol), formaldehyde 37% (10 ml, 134 mmol) and sodium hydroxide (100 mg) is refluxed for 7 days and is extracted with ethylacetate. Concentration in vacuo yields 1-benzyl-2-hydroxymethyl-imidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05296493 |
| Source dataset | uspto-grants-1994_03 |
| ORD ID | ord-577345ed1bed493fb40d458419d32569 |
| Source note | uspto-grants-1994_03 |