HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tributylstannane → 2-Ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tributylstannane | HCID 5948 | — |
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | 2-Ethoxycarbonylimino-3-(3-trifluoromethylpheny)-5-bromothiazoline | HCID 54096993 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-Ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazoline | HCID 54352089 | 75.8% |
Reaction Steps
A solution of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)-5-bromothiazoline (4.7 g), tributyltin hydride (6.9 g) and a catalytic amount of benzoyl peroxide in tetrahydrofuran (100 ml) was refluxed for 10 hours. The solvent was removed by distillation, and the residue was washed with hexane. Recrystallization from a mixture of hexane and ethanol gave 2.85 g of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)thiazoline (Compound (xii)).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05244863 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-c55f62cea29848c7bf7668db86abb1e9 |
| Source note | uspto-grants-1993_09 |