Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 548396Generated: October 24, 2026

2-Thiopheneglyoxylic acid → 6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-one

https://huagongshe.com/en/reaction/548396

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Thiopheneglyoxylic acidHCID 77694—
Reactant(3,4-Diaminophenyl)methanolHCID 12902832—
Product6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-oneHCID 21083665—

Reaction Steps

The quinoxalin-2-one of the present example is prepared with (3,4-Diamino-phenyl)-methanol and (thiophen-2-yl) oxo-acetic acid via the method described in Example 12 to afford 6-Hydroxymethyl-3-thiophen-2-yl-1H-quinoxalin-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUSRE042375E1
Source datasetuspto-grants-2011_05
ORD IDord-dccbeb8fdddb45fc8cdd39998918a598
Source noteuspto-grants-2011_05