HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Fluoronicotinic acid → HCID 21255180, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Fluoronicotinic acid | HCID 96089 | — |
| Reactant | 4-Thiazolecarboxylic acid | HCID 304271 | — |
| Product | HCID 21255180 | HCID 21255180 | 41.3% |
Reaction Steps
N-(2-Fluoronicotinoyl)thiazole-4-carboxylic acid is prepared as described in Example 5 from 11.03 g of thiazole-4-carboxylic acid and 11.7 g of 2-fluoronicotinic acid. 8.7 g of N-(2-fluoronicotinoyl)thiazole-4-carboxylic acid are thus obtained in the form of a cream solid. (Rf=0.33; thin layer chromatography on silica gel; eluent: ethyl acetate/acetic acid, 90/10 by volume).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06194426B1 |
| Source dataset | uspto-grants-2001_02 |
| ORD ID | ord-f02f7051a7cb493fb766c2df78543567 |
| Source note | uspto-grants-2001_02 |