HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydrazinopyridine → HCID 178479606, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydrazinopyridine | HCID 10909519 | — |
| Reactant | Ethyl 4-chloro-1,6-naphthyridine-3-carboxylate | HCID 17608818 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178479606 | HCID 178479606 | — |
Reaction Steps
A solution of 2.84 g of ethyl 4-chloro-1,6-naphthyridine-3-carboxylate and 1.35 g of 3-hydrazinopyridine in 36 ml of methanol is stirred at room temperature for 2.5 hours, then refluxed for 4.5 hours, then cooled in an ice bath and filtered. Collected solid is washed with methanol, then with ether to yield 2-(3-pyridyl)pyrazolo[4,3-c][1,6]naphthyridin-3-(5H)-one hydrochloride, m.p. 302°-305°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04560689 |
| Source dataset | uspto-grants-1985_12 |
| ORD ID | ord-563f916753134b21b4bc2f43d4041847 |
| Source note | uspto-grants-1985_12 |