HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 5,5-Dimethyl-2-formyl-1-(p-chlorophenyl)-hex-2-ene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 3,3-Dimethylbutanal | HCID 76335 | — |
| Reactant | 3-(4-Chlorophenyl)propanal | HCID 11535622 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5,5-Dimethyl-2-formyl-1-(p-chlorophenyl)-hex-2-ene | HCID 53955887 | — |
Reaction Steps
79 g (0.79 mol) of 3,3-dimethylbutyraldehyde are added to a solution of 10.5 g of 50% strength by weight aqueous NaOH in 500 ml of methanol, after which 123 g (0.73 mol) of p-chlorodihydrocinnamaldehyde are added dropwise at 34° C. The mixture is stirred for one hour and then neutralized with dilute sulfuric acid, the solution is evaporated down and the residue is then subjected to fractional distillation.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05134167 |
| Source dataset | uspto-grants-1992_07 |
| ORD ID | ord-028a180072164281b046302116495cc8 |
| Source note | uspto-grants-1992_07 |