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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 70421Generated: October 24, 2026

2-Amino-4-chlorobenzenethiol → N-(5-chloro-2-{[3-(dimethylamino)propyl]thio}phenyl)-1-benzofuran-2-sulfonamide

https://huagongshe.com/en/reaction/70421

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-chlorobenzenethiolHCID 12000—
Reactant3-(Dimethylamino)propyl chloride hydrochlorideHCID 94308—
Reactant1-Benzofuran-2-sulfonyl chlorideHCID 2795172—
ProductN-(5-chloro-2-{[3-(dimethylamino)propyl]thio}phenyl)-1-benzofuran-2-sulfonamideHCID 67972245—

Reaction Steps

Following General Procedure A, B, the title compound was prepared from 2-Amino-4-chloro-benzenethiol, (3-chloro-propyl)-dimethyl-amine hydrochloride and 1-benzofuran-2-sulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08822530B2
Source datasetuspto-grants-2014_09
ORD IDord-8328a27ea6f44d06a62e31affbdd206c
Source noteuspto-grants-2014_09