HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzonatate → Benzonatate calcium silicate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzonatate | HCID 7699 | — |
| Reactant | Dicalcium silicate | HCID 14941 | — |
| Product | Benzonatate calcium silicate | HCID 131733891 | — |
Reaction Steps
Calcium silicate was mixed at slow speed in a high shear granulator (Impeller: 250 rpm and Chopper: 3200 rpm). Benzonatate was added to it at slow speed (Impeller: 250 rpm and Chopper: 3200 rpm) at a rate of approximately 7 g/minute. The benzonatate-calcium silicate adsorbate granules formed were passed through 425 micron screen and assayed as described above for benzonatate content.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09180104B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-86c2dea6652e42f29d2fe0c294d480be |
| Source note | uspto-grants-2015_11 |