HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → Methyl 8-methyl-1,4-dioxaspiro[4.5]decane-8-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Lithium diisopropylamide | HCID 2724682 | — |
| Reactant | Methyl 1,4-dioxaspiro[4.5]decane-8-carboxylate | HCID 10845708 | — |
| Product | Methyl 8-methyl-1,4-dioxaspiro[4.5]decane-8-carboxylate | HCID 22591390 | — |
Reaction Steps
According to the process described in the literature (JP83-118577), methyl 1,4-dioxaspiro [4.5]decan-8-carboxylate was reacted with methyl iodide in the presence of LDA (lithium diisopropylamide) to obtain methyl 8-methyl-1,4-dioxaspiro [4.5]decan-8-carboxylate (the compound (1) of the above figure).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07138397B2 |
| Source dataset | uspto-grants-2006_11 |
| ORD ID | ord-afc59317940e481da20834cadb4f253c |
| Source note | uspto-grants-2006_11 |