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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 7983Generated: October 24, 2026

2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-one → 2-cinnamyl-6-(4-fluoro-3-methylphenyl)-4-hydroxymethyl-2H-pyridazin-3-one

https://huagongshe.com/en/reaction/7983

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-isobutyl-6-(2,4-difluorophenyl)-4-phthalimidomethyl-2H-pyridazin-3-oneHCID 21991587—
Reactant4-carboxy-2-cinnamyl-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-oneHCID 67213353—
Product2-cinnamyl-6-(4-fluoro-3-methylphenyl)-4-hydroxymethyl-2H-pyridazin-3-oneHCID 67213363—

Reaction Steps

Following the procedure of Example 1 (8), 4-carboxy-2-cinnamyl-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-one was reacted to yield the title compound as slightly yellow needles (yield: 20.1%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087606B2
Source datasetuspto-grants-2006_08
ORD IDord-535ad6d41210447d8a3bfdad5a29b12b
Source noteuspto-grants-2006_08