HuagongsheHuagongshe Chemistry Print Report · For research reference only
2H-Azepin-2-one, 3-aminohexahydro- → Tert-butyl 2-(3-amino-2-oxoazepan-1-yl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2H-Azepin-2-one, 3-aminohexahydro- | HCID 102463 | — |
| Reactant | Tert-butyl 2-iodoacetate | HCID 11021060 | — |
| Product | Tert-butyl 2-(3-amino-2-oxoazepan-1-yl)acetate | HCID 20132368 | — |
Reaction Steps
3-Aminoperhydro-2-azepinone (R. Pellegata, et al., Synthesis, 1978, 614-616) was alkylated with t-butyl iodoacetate as described in Example 1, Step B, to afford 1-t-butoxycarbonylmethyl-3-aminoperhydro-2-azepinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04757068 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-7894c250de9d49899b9da1c9725b1850 |
| Source note | uspto-grants-1988_07 |