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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8985Generated: October 24, 2026

5-Hydroxyindole-2-carboxylic acid → 3-(Dimethylaminophenylmethyl)-5-hydroxy-1H-indole-2-carboxylic Acid

https://huagongshe.com/en/reaction/8985

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Hydroxyindole-2-carboxylic acidHCID 88958—
ReactantMethanaminium, N-methyl-N-(phenylmethylene)-, chlorideHCID 11073839—
Product3-(Dimethylaminophenylmethyl)-5-hydroxy-1H-indole-2-carboxylic AcidHCID 9944519—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 5-hydroxy-1H-indole-2-carboxylic acid and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-e35ed87604f84e598d86fcf78697f08e
Source noteuspto-grants-2006_08