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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8993Generated: October 24, 2026

2-(3-Chloro-4-fluorophenyl)indole → {[2-(3-Chloro-4-fluorophenyl)-1H-indol-3-yl]-phenylmethyl}-dimethylamine

https://huagongshe.com/en/reaction/8993

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Chloro-4-fluorophenyl)indoleHCID 2736577—
ReactantMethanaminium, N-methyl-N-(phenylmethylene)-, chlorideHCID 11073839—
Product{[2-(3-Chloro-4-fluorophenyl)-1H-indol-3-yl]-phenylmethyl}-dimethylamineHCID 10156554—

Reaction Steps

The preparation was carried out in accordance with general synthesis instructions 4 from 2-(3-chloro-4-fluorophenyl)-1H-indole and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091220B2
Source datasetuspto-grants-2006_08
ORD IDord-a14dcd750a5843378b734cc81f27f6c0
Source noteuspto-grants-2006_08