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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 983854Generated: October 23, 2026

2,4-Dichlorobenzylidenemalononitrile → 5-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(4-methoxyphenyl)pyrimidin-4-amine

https://huagongshe.com/en/reaction/983854

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DichlorobenzylidenemalononitrileHCID 18089—
Reactant4-MethoxybenzenecarboximidamideHCID 229074—
Product5-(Aminomethyl)-6-(2,4-dichlorophenyl)-2-(4-methoxyphenyl)pyrimidin-4-amineHCID 10172601—

Reaction Steps

The title compound, MS: m/e=375.3 (M+H+), was prepared from 4-methoxybenzamidine and 2-(2,4-dichloro-benzylidene)-malononitrile in analogy to the process described in Example 11 as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06867205B2
Source datasetuspto-grants-2005_03
ORD IDord-9183a78c18c443b9ac121050a0944624
Source noteuspto-grants-2005_03