カナマイシン硫酸塩

Kanamycin A Sulfate

HCID 178956684CAS 133-92-6

基本情報

標準SMILES: NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O.O=S(=O)(O)O
InChIKey: OOYGSFOGFJDDHP-KMCOLRRFSA-N
分子式: C18H38N4O15S
平均分子量: 582.6 g/mol

概要

Kanamycin A sulfate is an aminoglycoside sulfate salt. It has a role as a geroprotector and an antibacterial drug. It contains a kanamycin A.

名称と識別子

優先名称: Kanamycin A Sulfate
IUPAC: (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
現地名: カナマイシン硫酸塩
英語名: KANAMYCIN SULFATE
分子式: C18H38N4O15S
分子量: 582.58

名称と別名

Kanamycin A sulfateKanamycin A sulphateDTXSID1047524J80EX28SMQEINECS 223-347-1(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acidCHEBI:6109DTXCID9027524KANAMYCIN A SULFATE [MI]KANAMYCIN SULFATE [USP-RS]KANAMYCIN SULFATE [USP MONOGRAPH]KANAMYCIN MONOSULFATE [EP MONOGRAPH]

名称をさらに表示

KANAMYCIN MONOSULFATEKANAMYCIN SULPHATEKANAMYCIN ACID SULFATEKAMYCINKANAMYCIN SULFATE WHITEKANAMYCIN MONO SULPHATEKANAMYCIN A SULFATE SALTKANAMYCIN MONOSULFATE SALTKanamycin sulfate soluble powder 12%KANAMYCIN SULFATE, STREPTOMYCES KANAMYCETICUS

KANAMYCIN SULFATE (USP-RS)KANAMYCIN SULFATE (USP MONOGRAPH)D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->4))-2-DEOXY-, SULFATE (1:1) (SALT)D-STREPTAMINE, O-3-AMINO-3-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->6)-O-(6-AMINO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSYL(1->4))-2-DEOXY-, SULPHATE (1:1) (SALT)D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl(1->6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl(1->4))-2-deoxy-, sulfate (1:1) (salt)KANAMYCIN MONOSULFATE (EP MONOGRAPH)Kanaplex(2R,3S,4S,5R,6R)-2-(aminomethyl)-6-((1R,2R,3S,4R,6S)-4,6-diamino-3-((2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl)oxy-2-hydroxycyclohexyl)oxyoxane-3,4,5-triol;sulfuric acid

データベース識別子

CAS: 133-92-6
ChEMBL: CHEMBL1446
ChEBI: CHEBI:6109
UNII: J80EX28SMQ
EC Number: 223-347-1、613-414-7

物性

構造計算による物性

極性表面積: 366 Å²
水素結合供与体数: 13
水素結合受容体数: 19
回転可能結合数: 6
重原子数: 38
形式電荷: 0
複雑度: 720

実験および物理化学的性質

Human Drugs · 2 件

FDA approved drugs -> Active ingredient

Animal DrugsActive Ingredients (Kanamycin Sulfate) -> FDA Greenbook

Collision Cross Section221.1 Å² [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

物理化学的性質

貯蔵温度: 2 · 2-8°C
溶解性: 2 O: · H2O: 原液として 10 ～ 50 mg/mL。ストックソリューションは 2 ～ 8 ° C で保存する必要があります。 37℃で5日間安定。
外見: 粉
PH: pH (50g/l, 25℃) : 6.0～7.5

安全と法規制

GHS分類

GHS Classification · 6 件

This chemical does not meet GHS hazard criteria for 1% (1 of 96) of reports.

Danger

H360 (69.8%): May damage fertility or the unborn child [Danger Reproductive toxicity]

P203, P260, P264, P270, P273, P280, P318, P319, P391, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 96 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

危険有害性情報

Hazard Classes and Categories · 2 件

Repr. 1B (69.8%)

Repr. 1B (100%)

安全データ

wgk: 3
rtecs: NZ3225030
safety_code: 22-24/25

化学と産業

用途と製造

Use ClassificationAnimal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

応用分野 · 3 件

用途細胞生物学研究用。

用途薬剤耐性因子の研究、培養液添加剤。

使用Antibacterial Kantrex (Apothecon).

サプライヤー22 社

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杭州鼎燕化工有限公司13588754826 13588754826 · [email protected]