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4,5-Dichlorophthalic anhydride → Ethyl 3-(5,6-dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4,5-Dichlorophthalic anhydride | HCID 70334 | — |
| 反応物 | Ethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate | HCID 21982228 | — |
| 生成物 | Ethyl 3-(5,6-dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate | HCID 21982181 | — |
反応手順
Ethyl 3-(5,6-dichloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.66 g, 50%) in the same manner as described in the above example 5 (20) from ethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (0.60 g, 3.25 mmol) and 4,5-dichlorophthalic anhydride (0.85 g, 3.90 mmol), and the obtained product was identified with the following NMR data.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07094908B2 |
| 出典データセット | uspto-grants-2006_08 |
| ORD ID | ord-b65c8bbe15784ca3b285bbca9b865f1d |
| 出典メモ | uspto-grants-2006_08 |