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6-Nitroveratryl alcohol → 4,5-Dimethoxy-2-nitrobenzyl hexadecanesulfonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Nitroveratryl alcohol | HCID 66097 | — |
| 反応物 | 1-Hexadecanesulfonyl chloride | HCID 96923 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 溶媒 | Dicyclohexylamine | HCID 7582 | — |
| 生成物 | 4,5-Dimethoxy-2-nitrobenzyl hexadecanesulfonate | HCID 53792646 | — |
反応手順
To a solution of 5.33 g (0.025 mol) of 4,5-dimethoxy-2-nitrobenzyl alcohol and 8.15 g (0.025 mol) hexadecanesulfonyl chloride in 100 ml of acetone, dicyclohexylamine (5 ml, slight excess) was added via motor driven syringe over 30 minutes. After the addition was complete, the reaction was stirred an additional 30 minutes. The precipitated dicyclohexylamine hydrochloride was removed by filtration and the acetone filtrate reduced in volume in vacuo until most of the product had precipitated (yield 9.5 g, m.p. 81°-82° C.).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04980096 |
| 出典データセット | uspto-grants-1990_12 |
| ORD ID | ord-0bda839b85f6458e8c089dd31d4efe42 |
| 出典メモ | uspto-grants-1990_12 |