化工社化工社 化学情報印刷レポート · 研究参考用
Hydroxyamine hydrochloride → 5-(2,4-Dichlorophenyl)-2-furancarboxaldehyde Oxime
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 反応物 | 5-(2,4-Dichlorophenyl)-2-furaldehyde | HCID 674998 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 5-(2,4-Dichlorophenyl)-2-furancarboxaldehyde Oxime | HCID 73164714 | — |
反応手順
A mixture of 5-(2,4-dichlorophenyl)-2-furancarboxaldehyde (635 g, 2.63 moles), anhydrous sodium acetate (432 g, 5.26 moles), hydroxylamine hydrochloride (366 g, 5.26 moles), SDA #30 (9184 ml) and water (918 ml), was refluxed for 51/3 hours and allowed to stand overnight. The mixture was added to ice/H2O (42 liters), stirred 1 hour and filtered. The grayish-tan solid was washed with water (10 liters), filtered and dried at 65° to 660 g (98%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04336199 |
| 出典データセット | uspto-grants-1982_06 |
| ORD ID | ord-f31b852d434643aaa384fb2fff829726 |
| 出典メモ | uspto-grants-1982_06 |