関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | (S)-Benzyl (2-oxotetrahydrofuran-3-yl)carbamate | HCID 489185 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | Methyl ((benzyloxy)carbonyl)-L-homoserinate | HCID 53977437 | — |
反応手順
To the compound (500 mg) obtained in Step 1 were added methanol (5 ml) and conc. sulfuric acid (30 μl), and the mixture was stirred overnight at 60° C. To the reaction mixture was further added sodium hydrogen carbonate (250 mg), and the mixture was stirred at room temperature for 2 hrs. After celite filtration of the reaction mixture, the solvent was evaporated to give the title compound as a crude product.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07728005B2 |
|---|
| 出典データセット | uspto-grants-2010_06 |
|---|
| ORD ID | ord-223c89daee13463498f015655b9c9c34 |
|---|
| 出典メモ | uspto-grants-2010_06 |
|---|
