化工社化工社 化学情報印刷レポート · 研究参考用
Dimethyl Sulfate → HCID 15125726、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethyl Sulfate | HCID 6497 | — |
| 反応物 | Methyl formate | HCID 7865 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 3-Phenoxyphenol | HCID 12842 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 反応物 | 2-Bromobenzaldehyde | HCID 81129 | — |
| 反応物 | HCID 10861730 | HCID 10861730 | — |
| 反応物 | Methyl 2-(3-methoxyphenoxy)phenylacetate | HCID 14620154 | — |
| 反応物 | (E)-methyl 2-[2-(3-hydroxyphenoxy)phenyl]-3-methoxypropenoate | HCID 14620157 | — |
| 生成物 | HCID 15125726 | HCID 15125726 | — |
反応手順
Methyl 2-(3-phenoxyphenoxy)phenylacetate was prepared from 3-phenoxyphenol and 2-bromobenzaldehyde by the steps described in Example 1 for the preparation of methyl 2-(3-methoxyphenoxy)phenylacetate. This was the converted into (E)-methyl 3-methoxy-2-[2-(3-phenoxyphenoxy) phenyl]propenoate [1H n.m.r (250 MHz) 3.61 (3H, s), 3.78 (3H, s), 6.68-7.35 (13H, m), 7.48 (1H, s) ppm] using sodium hydride and methyl formate, and then potassium carbonate and dimethyl sulphate, using the procedure described in Example 1 for the preparation of (E)-methyl 2-[2-(3-hydroxyphenoxy)phenyl]-3-methoxypropenoate, except that just 2 equivalents of sodium hydride were used in this case.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05468857 |
| 出典データセット | uspto-grants-1995_11 |
| ORD ID | ord-5570be487ca14746a87360442f67b0ac |
| 出典メモ | uspto-grants-1995_11 |