化工社化工社 化学情報印刷レポート · 研究参考用
Ethyl indole-2-carboxylate → 7-Fluoro-1-methylindole-3-carboxaldehyde
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethyl indole-2-carboxylate | HCID 73125 | — |
| 反応物 | 7-Fluoro-1H-indole-3-carbaldehyde | HCID 22139120 | — |
| 生成物 | 7-Fluoro-1-methylindole-3-carboxaldehyde | HCID 22139037 | 43% |
反応手順
According to the procedure of Preparation 9 (a), except substituting 7-fluoro-1H-indole-3-carboxaldehyde (0.5 g, 3.1 mmole) for the ethyl indole-2-carboxylate, the title compound (0.23 g, 43%) was prepared as a viscous oil: MS (ES) m/e 178 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07879872B2 |
| 出典データセット | uspto-grants-2011_02 |
| ORD ID | ord-27a67b25279a4b50818e182649272ed9 |
| 出典メモ | uspto-grants-2011_02 |