化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Dithionite → 2,2'-Bithiophene-5-carboxylic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Dithionite | HCID 24489 | — |
| 反応物 | 5-Acetyl-2,2'-bithienyl | HCID 606422 | — |
| 反応物 | Sodium Hypochlorite | HCID 23665760 | — |
| 生成物 | 2,2'-Bithiophene-5-carboxylic acid | HCID 150965 | — |
反応手順
35 ml of NaOCl solution was heated to 55° C. and 5-acetyl-2,2'-bithiophene was then added and stirred at 60°-70° C. for 2 hours. Then the reaction solution was cooled by ice bath and aqueous Na2S2O4 solution was added for removing the residual NaOCl. The reaction mixture was acidified by HCl(aq) and filtered to obtain golden product. The product was further recrystallized with 95% ethanol. The melting point of the product was 183-184%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05602170 |
| 出典データセット | uspto-grants-1997_02 |
| ORD ID | ord-560a5760db2f4c50a9267b1500ae651c |
| 出典メモ | uspto-grants-1997_02 |