関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrogen Bromide | HCID 260 | — |
| 反応物 | Bromine | HCID 24408 | — |
| 反応物 | 4-Ethyl-2-nitroaniline | HCID 251674 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 2-Bromo-4-ethyl-6-nitroaniline | HCID 19973468 | — |
反応手順
5-Ethyl-7-bromo-4-[benzenesulfonimide]-1,4-dihydroquinoline-2-carboxylic acid, ethyl ester ##STR24## Mix 4-ethyl-2-nitroaniline (16.6g, 0.1mol) in water (400mL) and add 48% hydrobromic acid (1kg). Add bromine (16g, 0.1mol) with stirring and stir for 1 hour. Dilute to 2L and cool to 7° C. Filter, wash with water and dry to give 4-ethyl-2-nitro-6-bromoaniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05606063 |
|---|
| 出典データセット | uspto-grants-1997_02 |
|---|
| ORD ID | ord-830a3608bdd9453eba333810836ebcfd |
|---|
| 出典メモ | uspto-grants-1997_02 |
|---|
