関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetone, oxime | HCID 67180 | — |
| 反応物 | 4-{3-[4-(1-Chloroethyl)phenylthio]-5-fluorophenyl}-4-methoxytetrahydropyran | HCID 19379931 | — |
| 生成物 | HCID 9909885 | HCID 9909885 | 58% |
反応手順
Using an analogous procedure to that described in Example 1 except that the reactants were heated to 60° C. for 2 hours, acetone oxime was reacted with 4-{3-[4-(1-chloroethyl)phenylthio]-5-fluorophenyl}-4-methoxytetrahydropyran to give acetone O-{4-[5-fluoro-3-(4-methoxytetrahydropyran-4-yl)phenylthio)-α-methylbenzyl}oxime as an oil in 58% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05376680 |
|---|
| 出典データセット | uspto-grants-1994_12 |
|---|
| ORD ID | ord-eb32913a49604aa78cf550693e028e28 |
|---|
| 出典メモ | uspto-grants-1994_12 |
|---|
