化工社化工社 化学情報印刷レポート · 研究参考用
Butanal → 4-nitro-2-propyl-1H-benzoimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Butanal | HCID 261 | — |
| 反応物 | Ammonium Hydroxide | HCID 14923 | — |
| 反応物 | 3-Nitro-1,2-phenylenediamine | HCID 4359525 | — |
| 溶媒 | Phosphorus oxychloride | HCID 24813 | — |
| 生成物 | 4-nitro-2-propyl-1H-benzoimidazole | HCID 10774608 | 87.2% |
反応手順
3-Nitro-benzene-1,2-diamine (1.0 g, 6.54 mmol) and butyraldehyde (630 μL, 7.19 mmol) were stirred in POCl3 (10 mL) at 85° C. for 3 hours. The reaction was cooled to ambient temperature and poured over ice. The resulting mixture was basified with NH4OH. The precipitate was filtered and washed with ice water to give 1.17 g of the sub-title compound that was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07732618B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-6c54cbcdd50b4c60819d061a284331fb |
| 出典メモ | uspto-grants-2010_06 |