化工社化工社 化学情報印刷レポート · 研究参考用
Hydrogen Cyanide → 4-Hydroxy-3-methoxyphenylacetonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrogen Cyanide | HCID 768 | — |
| 反応物 | Vanillyl alcohol | HCID 62348 | — |
| 溶媒 | Dimethyl Sulfoxide | HCID 679 | — |
| 生成物 | 4-Hydroxy-3-methoxyphenylacetonitrile | HCID 78220 | — |
反応手順
185g of 3-methoxy-4-hydroxybenzyl alcohol are dissolved in 1,250 ml of DMSO and 35g of anhydrous hydrocyanic acid are passed in over the course of 1 hour at 125°C. The mixture is then stirred for a further 2 hours, and worked up as indicated above. The yield was 160.5g (82% of theory).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03983160 |
| 出典データセット | uspto-grants-1976_09 |
| ORD ID | ord-70f38d4a54f142658a425b4605e80135 |
| 出典メモ | uspto-grants-1976_09 |