化工社化工社 化学情報印刷レポート · 研究参考用
1-(3-Azidopropyl)-4-fluorobenzene → 3-(4-Fluorophenyl)propan-1-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(3-Azidopropyl)-4-fluorobenzene | HCID 58997701 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-(4-Fluorophenyl)propan-1-amine | HCID 6483796 | 57.1% |
反応手順
The product from step e (0.79 g, 6.4 mmol) was dissolved in 100 mL of MeOH and added carefully to 0.20 g of 10% Pd/C under N2. The mixture was hydrogenated in a Parr shaker at 50 PSI overnight. Filtration through fiberglass filter paper under N2 and under vacuum yielded 0.56 g of a clear colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07291744B2 |
| 出典データセット | uspto-grants-2007_11 |
| ORD ID | ord-e98aa9fc6dbc41d6b7b745af3d109ccc |
| 出典メモ | uspto-grants-2007_11 |