関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethyl phenylphosphonite | HCID 76277 | — |
| 反応物 | 2,6-Di-tert-butyl-4-(chloromethyl)phenol | HCID 12378601 | — |
| 生成物 | (3,5-Di-tert-butyl-4-hydroxy-benzyl)-phenyl-phosphinic acid methyl ester | HCID 57909093 | 83% |
反応手順
A mixture of 5 grams (29 mmol) of dimethylphenylphosphonite with 7.5 grams (29 mmol) of 3,5-di-tert-butyl-4-hydroxybenzyl chloride (CAS REG # 955-01-1) is heated at 110° C. for 1 hour and cooled to obtain a white solid. The resultant solid is crystallized from 100 mL of hexane to give 9 grams (83% yield) of (3,5-di-tert-butyl-4-hydroxy-benzyl)-phenyl-phosphinic acid methyl ester as a white solid mp 112-114° C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US08030435B2 |
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| 出典データセット | uspto-grants-2011_10 |
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| ORD ID | ord-580a61d30f84455793d0fa9230e72625 |
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| 出典メモ | uspto-grants-2011_10 |
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