Sulfuryl chloride → Bis-(2-fluorophenyl)disulfide

HRID 1677877

反応式

HRID 1677877 の反応式
S(Cl)(Cl)(=O)=O.[F:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[SH:13]>C(Cl)Cl>[F:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[S:13][S:13][C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=1[F:6]

参加物

4

反応物 2

HCID 24648Sulfuryl chlorideHCID 5202162-Fluorothiophenol

生成物 1

HCID 14740277Bis-(2-fluorophenyl)disulfide

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Sulfuryl chloride (0.7 ml) was added dropwise to a solution of 2-fluorobenzenethiol (1.5 ml) in DCM (20 ml) at 0° C. The reaction mixture was stirred for 30 min, then concentrated under reduced pressure. The residue was purified by chromatography on silica eluting with isohexane to give the sub-title compound as an oil, yield 1.7 g.

後処理

  1. concentrationconcentrated under reduced pressure
  2. customThe residue was purified by chromatography on silica eluting with isohexane

出典と根拠

ORDレコード
ord-03f5957e82d74073919f51f3de5d4130
出典データセット
uspto-grants-2011_08
特許番号
US08008350B2

関連ノート

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