化工社化工社 化学情報印刷レポート · 研究参考用
Methyl acetoacetate → 3-Furancarboxylic acid, 2,5-dimethyl-, methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl acetoacetate | HCID 7757 | — |
| 反応物 | 2-(Acetyloxy)propanal | HCID 90728 | — |
| 触媒 | Iron | HCID 23925 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 3-Furancarboxylic acid, 2,5-dimethyl-, methyl ester | HCID 80248 | — |
反応手順
40 parts by weight of iron-III chloride and 136 parts by weight of 85 percent strength α-acetoxypropionaldehyde are added successively to a solution of 150 parts by weight of methyl acetoacetate in 120 parts by weight of methanol. The mixture, which becomes warm, is then refluxed for 2 hours. When it has cooled, the reaction solution is washed with water and distilled. 127 g of 2,5-dimethylfuran-3-carboxylic acid methyl ester are obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04207243 |
| 出典データセット | uspto-grants-1980_06 |
| ORD ID | ord-a86d7762caed427391b66ee59855b844 |
| 出典メモ | uspto-grants-1980_06 |