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3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carbonyl chloride → 3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}propyl 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carbonyl chloride | HCID 2736581 | — |
| 反応物 | N-{3-[1-(3-Hydroxypropyl)-4-piperidinyl]phenyl}-2-methylpropanamide | HCID 22048877 | — |
| 生成物 | 3-{4-[3-(Isobutyrylamino)phenyl]-1-piperidinyl}propyl 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarboxylate | HCID 22049124 | — |
反応手順
Prepared by Procedure Q1 and Scheme C2 (TEA) using N-{3-[1-(3-hydroxypropyl)-4-piperidinyl]phenyl}-2-methylpropanamide and 3-(2-chloro-6-fluorophenyl)-5-methyl-4-isoxazolecarbonyl chloride: ESMS m/e: 542.2 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07067534B1 |
| 出典データセット | uspto-grants-2006_06 |
| ORD ID | ord-9d2c83cfeadd4509bcc2edd2342525f9 |
| 出典メモ | uspto-grants-2006_06 |