化工社化工社 化学情報印刷レポート · 研究参考用
Methyl iodide → N,N,N-trimethyl-o-nitrophenylmethanaminium iodide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Methyl iodide | HCID 6328 | — |
| 反応物 | N,N-dimethyl-2-nitrobenzylamine | HCID 420851 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | N,N,N-trimethyl-o-nitrophenylmethanaminium iodide | HCID 86676882 | 167.6% |
反応手順
The mixture of 57b (0.18 g, 0.5 mmol) and iodomethane (0.71 g, 5 mmol) in anhydrous CH2Cl2 (5 mL) was stirred for 12 h at r. t., then added additional iodomethane (0.71 g, 5 mmol) and continuously stirred for 12 h. After evaporation, the residue was dispensed with CH2Cl2 and filtered to give 58b (0.27 g, 84%) as yellow solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08962670B2 |
| 出典データセット | uspto-grants-2015_02 |
| ORD ID | ord-71eb6fe81351474fbb2f78ba04d7094d |
| 出典メモ | uspto-grants-2015_02 |