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2-Amino-5-chlorobenzophenone → N-(2-Benzoyl-4-chloro-phenyl)-4-methanesulfonyl-benzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Amino-5-chlorobenzophenone | HCID 12870 | — |
| 反応物 | 4-Methanesulfonylbenzene-1-sulfonyl chloride | HCID 2735182 | — |
| 生成物 | N-(2-Benzoyl-4-chloro-phenyl)-4-methanesulfonyl-benzenesulfonamide | HCID 11408313 | — |
反応手順
The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 115 mg of (2-amino-5-chloro-phenyl)-phenyl-methanone and 127 mg of 4-Methanesulfonyl-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 2.92 (s, 3H), 7.34 (m, 3H), 7.434 (m, 2H), 7.51 (dd, 1H, J=8.8 Hz, 2.4 Hz), 7.60 (m, 1H), 7.75 (d, 1H, J=8.8 Hz), 7.80-7.86 (m, 4H), 9.86 (b, 1H). MS: m/z 450.9 (M++1).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07741519B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-4fd6963b18fb454382e486e6af2332c3 |
| 出典メモ | uspto-grants-2010_06 |