関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Ethylamine | HCID 6341 | — |
| 反応物 | Tributylamine | HCID 7622 | — |
| 反応物 | Acetylacetone | HCID 31261 | — |
| 反応物 | 5-Methyl hydrogen L-glutamate | HCID 68662 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | L-Theanine | HCID 439378 | 66.7% |
反応手順
First, 5.0 g (31 mmol) of L-glutamic acid-γ-methyl ester was suspended in 15 mL of methanol. To this, 3.4 g (34 mmol) of acetylacetone and 5.7 g (31 mmol) of tri-n-butylamine were added. The mixture was heated at 60° C. for 2 hours. Subsequently, 20 g (310 mmol) of 70% ethylamine was added to the mixture and the same procedure as in Example 1 was performed to obtain 3.6 g of theanine (yield: 66.7%). The obtained theanine had the same purity as high as in Example 1.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08178722B2 |
|---|
| 出典データセット | uspto-grants-2012_05 |
|---|
| ORD ID | ord-bf2f1eabb7e846139a59933d931e06a1 |
|---|
| 出典メモ | uspto-grants-2012_05 |
|---|
