化工社化工社 化学情報印刷レポート · 研究参考用
4-Pyrrolidinopyridine → 4-Hydrazino-6-(4-pyrrolidin-1-ylpiperidin-1-yl)pyrimidine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Pyrrolidinopyridine | HCID 75567 | — |
| 反応物 | 4-Chloro-6-hydrazinylpyrimidine | HCID 247222 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | 4-Hydrazino-6-(4-pyrrolidin-1-ylpiperidin-1-yl)pyrimidine | HCID 59603700 | — |
反応手順
A mixture of 2.0 g (13.8 mmol) of the compound from Example 7A and 4.3 g (27.7 mmol) 4-pyrrolidin-1-ylpyridine is stirred in 20 ml water at 100° C. for 16 h. The solid which has precipitated out is filtered off, washed first with ethanol and then with diethyl ether and dried in vacuo.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08389520B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-5630869ccbe24d82811f7065e5f16ce0 |
| 出典メモ | uspto-grants-2013_03 |