化工社化工社 化学情報印刷レポート · 研究参考用
N-(2-methoxy-4-nitrophenyl)methanesulfonamide → N-(4-amino-2-methoxyphenyl)methanesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(2-methoxy-4-nitrophenyl)methanesulfonamide | HCID 3298129 | — |
| 触媒 | Palladium | HCID 23938 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | N-(4-amino-2-methoxyphenyl)methanesulfonamide | HCID 12254686 | — |
反応手順
A solution of 2-methoxy-4-nitro-methanesulfonylaminobenzene (1 g) in methanol (20 ml) containing palladium on carbon (10%, 100 mg) was stirred at RT under hydrogen for 48 h. The mixture was filtered through celite then evaporated to give 2-methoxy-4-amino-methanesulfonylaminobenzene as a brown gum. This was used without purification in the following reaction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07745490B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-b1e54b3518a942d8962e71b836721636 |
| 出典メモ | uspto-grants-2010_06 |