化工社化工社 化学情報印刷レポート · 研究参考用
Isoflurane → Desflurane
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Isoflurane | HCID 3763 | — |
| 反応物 | Hydrofluoric Acid | HCID 14917 | — |
| 反応物 | Desflurane | HCID 42113 | — |
| 触媒 | Chromia | HCID 517277 | — |
| 生成物 | Desflurane | HCID 42113 | — |
| 生成物 | Desflurane Hydrogen Fluoride | HCID 86625408 | — |
反応手順
It has been found that fractional distillation of a crude reaction mixture obtained in the manufacture of desflurane, for example, by reacting hydrogen fluoride with isoflurane over a bed of chromia catalyst, results in the removal of desflurane in the form of a desflurane/hydrogen fluoride azeotrope that boils below the boiling point of hydrogen fluoride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08283500B2 |
| 出典データセット | uspto-grants-2012_10 |
| ORD ID | ord-b089b2ff411140a2a8ecf40828639600 |
| 出典メモ | uspto-grants-2012_10 |