関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Sodium Acetate | HCID 517045 | — |
| 反応物 | Trivinyl(3-chloropropyl)silane | HCID 23630656 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 3-Acetoxypropyltrivinylsilane | HCID 57945596 | 76% |
反応手順
As shown in Reaction Scheme 24, 3-chloropropyltrivinylsilane (1.0 g, 5.35 mmol) and sodium acetate (0.87 g, 10.7 mmol) were dissolved in 17 mL of dimethylformamide (DMF), and the reaction mixture was heated at 120° C. for 12 hours. After the reaction, the organic layer was separated after addition of distilled water and ether. The organic layer was dried over MgSO4, concentrated by evaporation of solvent, and the resulting residue was purified by column chromatography (n-Hex: EA=10:1, Rf=0.4) to give 855 mg (76% yield) of pure 3-acetoxypropyltrivinylsilane.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08197903B2 |
|---|
| 出典データセット | uspto-grants-2012_06 |
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| ORD ID | ord-672dfd5c3911452085a6ee1da2c6cf62 |
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| 出典メモ | uspto-grants-2012_06 |
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