関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | O-Phenylenediamine | HCID 7243 | — |
| 反応物 | Isatoic Anhydride | HCID 8359 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | Benzo[b][1,4]benzodiazepin-6-one | HCID 19781529 | 96% |
反応手順
A mixture of isatoic anhydride (1 mol) and 1,2 phenylenediamine (1.1 mol) in aglacial acetic acid (60%) was heated at 75° C. for 3 hrs. The resulting mixture was diluted with water and solid filtered to obtained dibenzo[b,e][1,4]-diazepine-11-one in 96% yield.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08202989B2 |
|---|
| 出典データセット | uspto-grants-2012_06 |
|---|
| ORD ID | ord-2936c68d6a464830925ee60bd4de99dd |
|---|
| 出典メモ | uspto-grants-2012_06 |
|---|
