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Potassium Carbonate → Methyl 4-(octyloxy)-2-[(pent-4-en-1-yl)oxy]benzoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 1-Pentene, 5-bromo- | HCID 70704 | — |
| 反応物 | Methyl 2-hydroxy-4-octyloxybenzoate | HCID 11536459 | — |
| 溶媒 | Methyl Ethyl Ketone | HCID 6569 | — |
| 生成物 | Methyl 4-(octyloxy)-2-[(pent-4-en-1-yl)oxy]benzoate | HCID 69309676 | — |
反応手順
A mixture of 66.1 g (0.234 mol) of 2-Hydroxy-4-octyloxy benzoic acid methyl ester obtained in Step 1, 44.7 g (0.30 mol) of 5-Bromopent-1-ene, 207 g (1.5 mol) of K2CO3 and 700 mL of dry butanone is refluxed for 24 h, then allowed to return to room temperature. The reaction mixture is filtered and the butanone is distilled off under reduced pressure. After drying the residue under vacuum a slightly yellow oil (77.5 g, 95%) is obtained, which can be used in the next step without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07416682B2 |
| 出典データセット | uspto-grants-2008_08 |
| ORD ID | ord-de0158ce895c4d5dafc86eded8a4cfff |
| 出典メモ | uspto-grants-2008_08 |