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Sulfuric Acid → N-ethyl-N-(beta-hydroxyethyl)-3-methyl-4-nitrosoaniline sulfate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | 2-(N-ethyl-m-toluidino)ethanol | HCID 7067 | — |
| 反応物 | Ethanol, 2-((4-amino-3-methylphenyl)ethylamino)-, sulfate (1:1) | HCID 91579 | — |
| 生成物 | N-ethyl-N-(beta-hydroxyethyl)-3-methyl-4-nitrosoaniline sulfate | HCID 22071911 | — |
反応手順
A process for producing 4-amino-3-methyl-N-ethyl-N-(β-hydroxyethyl)aniline sulfate which comprises nitrosating N-ethyl-N-(β-hydroxyethyl)-m-toluidine with an alkyl nitrite in an aqueous alcohol solution containing 30-90% by volume of the alcohol and about 0.5 to about 1 mole of sulfuric acid per mole of the N-ethyl-N-(β-hydroxyethyl)-m-toluidine to form N-ethyl-N-(β-hydroxyethyl)-3-methyl-4-nitrosoaniline sulfate, and catalytically hydrogenating the N-ethyl-N-(β-hydroxyethyl)-3-methyl-4-nitrosoaniline sulfate.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05475140 |
| 出典データセット | uspto-grants-1995_12 |
| ORD ID | ord-1036ecad19944a72b82fe72a1acd8de4 |
| 出典メモ | uspto-grants-1995_12 |