化工社化工社 化学情報印刷レポート · 研究参考用
Triethylamine → [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl methanesulfonate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Methanesulfonyl chloride | HCID 31297 | — |
| 反応物 | (R)-Solketal | HCID 736056 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl methanesulfonate | HCID 24903512 | — |
反応手順
The (R)-(−)-2,2-dimethyl-1,3-dioxolane-4-methanol (Aldrich, 0.38 mL, 3.1 mmol), triethylamine (0.85 mL, 6.1 mmol), and methanesulfonyl chloride (0.31 mL, 4.1 mmol) in 10 mL THF were processed as described in Example 1C to give the title compound that was used directly in the next reaction.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07560481B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-e158575da21c4b91b9a0a6b159c58000 |
| 出典メモ | uspto-grants-2009_07 |